12-Hydroxyeicosatetraenoic acid

12-Hydroxyeicosatetraenoic acid

IUPAC name (5Z,8Z,10E,12S,14Z)-12-Hydroxyicosa-5,8,10,14-tetraenoic acid
Other names 12-HETE; 12(S)-HETE
Identifiers
CAS number	54397-83-0
PubChem	5283155
ChemSpider	4446279^Y
ChEBI	CHEBI:34146^Y
Jmol-3D images	Image 1 Image 2
SMILES CCCCC/C=C\C[C@@H](/C=C/C=C\C/C=C\CCCC(=O)O)O O=C(O)CCC\C=C/C/C=C\C=C\[C@@H](O)C\C=C/CCCCC
InChI InChI=1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1^Y Key: ZNHVWPKMFKADKW-LQWMCKPYSA-N^Y InChI=1/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+/t19-/m0/s1 Key: ZNHVWPKMFKADKW-LQWMCKPYBD
Properties
Molecular formula	C₂₀H₃₂O₃
Molar mass	320.47 g mol⁻¹
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

12-Hydroxyeicosatetraenoic acid (12-HETE) is an eicosanoid. It is a metabolite of arachidonic acid produced by the action of the enzyme arachidonate 12-lipoxygenase. 12-HETE is a highly selective ligand used to label mu opioid receptors.^[1]

References